The primary paradigm of healthcare in the modern era is drug use. The most common medication for pain and fever is Paracetamol. Even though paracetamol adverse effects are uncommon in India, they occasionally can result in conditions that are fatal. Unfavorable medication reactions like Stevens-Johnson syndrome (SJS) have the potential to be fatal. There are only very few reports regarding paracetamol induced SJS. We describe a case of SJS that was brought on by the use of paracetamol. The clinical features and medical management of the patient was briefly described.