A Prospective Observational Study on Occurrence and Recurrence of Ischemic Stroke in Patient on Treatment with Anti-Hypertensives

Asian Journal of Pharmaceutical and Health Sciences,2022,12,3,2683-2688.
Published:December 2022
Type:Research Article
Author(s) affiliations:

Andhuvan Gandhi1*, Sherin Shaji2, Shri Vishwapal S2 , Shyam Nikethen G2 ,Subhasini S2 ,Asokan.K3

1Department of Pharmacy Practice, College of Pharmacy, Sri Ramakrishna Institute of Paramedical sciences, Coimbatore, Tamil Nadu, India.

2Department of Neurology, Sri Ramakrishna Multi-Specialty Hospital, Coimbatore, Tamil Nadu, India.


Stroke represents a leading cause of mortality and the first cause of functional disability. Nearly a 1.8million person suffers from stroke every year in India. The major risk factors of strokes include Hypertension, Diabetes Mellitus, Alcohol and Smoking. Modified Rankin Scale (mRS) measures the degree of disability. To find out Stroke Occurrence and Recurrence in patients on treatment with Anti- Hypertensive with their disability score.The patients were included based on the inclusion and exclusion criteria. An informed consent was prepared. Patient history and clinical data were collected. The data collected was documented and the results were analysed based on the outcome measures.The Age category of 45-65years had the most incidences to ischemic stroke with 40.5% and 47.8%, involving male population of 67.4% and 69.57% of occurrent and recurrent stroke. Tobacco consumption was the leading social history involved. Diabetes with hypertension was the major co-morbidity associated. CCBs were the most frequently prescribed antihypertensive with 26.19% & 37.5% incidence in occurrence and recurrence stroke respectively. The study shows that CCBs are the highly prescribed class of anti-hypertensives followed by CCB+DIURETICS and Beta blockers for prevention of hypertension. Diabetes with hypertension, tobacco usage are the various factors influencing risk for ischemic stroke. mRS score of 3 is the common disability seen in the stroke patients in this study

Type of incidence vs percentage patient population of different Modified Rankin scale scores