Extensive Pulmonary Cryptococcosis in an HIV Infected Person: A Case Report

Asian Journal of Pharmaceutical and Health Sciences,2017,7,3,1655-1657.
Published:September 2017
Type:Case Report
Author(s) affiliations:

Ayandip Nandi1, Rudrajit Paul*1, Debaditya Roy1, Ratul Ghosh1, Tanmay Jyoti Sau1, Chirantan Majumdar1, Jayati Mondal2

1Department of Pathology, Medical College Kolkata. 88, College Street, Kolkata- 700073, West Bengal, India.

2Chittaranjan Seva Sadan, Kolkata, West Bengal, India.


Cryptococcus is a fungus whose disease manifestations are usually found in immuno compromised persons. In HIV infection, cryptococcal infection is usually found in the central nervous system. However, other sites like the lungs are also rarely affected. We here report the case of a 45 year old HIV infected male, who was admitted with severe dyspnoea and weight loss. HRCT thorax revealed bilateral pulmonary consolidation with cavitation. FNAC from the lung lesions revealed large capsulated budding yeast cells, suggestive of Cryptococcus. Serum cryptococcal antigen was also positive. The patient, unfortunately, could not be saved despite anti-fungal therapy.

Microscopic picture of pulmonary Fine needle aspiration showing yeast cells visible in 10× magnification