A Case Study of Early Brain Metastasis in Locally Advanced Breast Cancer

Asian Journal of Pharmaceutical and Health Sciences,2016,6,2,1483-1484.
Published:June 30
Type:Case Report
Author(s) affiliations:

Pooja Gupta1*, Rahat Hadi1, Ashish Singhal2, Ramakant Tiwari1

1Department of Radiation Oncology, 2Department of Surgical Oncology

Dr. Ram Manohar Lohia Institute of Medical Sciences, VibhutiKhand, Gomti Nagar, Lucknow- 226010, Uttar Pradesh, India.


Breast cancer metastases to the central nervous system (CNS) include the clinically distinct situations of multiple brain metastases (78%), solitary brain metastasis (14%), and leptomeningeal metastases (8%). CNS metastases reported till now in 10%16% of stage IV patients (pts.) while in ~30% of pts. in autopsy series. Here we present an interesting case report of 33years old female diagnosed as triple receptor-negative invasive ductal carcinoma right breast(T3N1M0), treated with neoadjuvant chemotherapy followed by surgery, pt. was due for adjuvant radiotherapy which was scheduled 1 month postsurgery but in the meantime pt. developed brain metastases in left temporo-parietal region.

CECT scan axial section showing multiple brain metastases in left frontal